1941 The location of Pueblo Depot Activity (PUDA) was selected in response to the acceleration of national defense efforts prior to United States intervention in World War II (WWII). PUDA covers 22,654 acres of rolling prairie lands and has a mixture of buildings and other structures, with open and undeveloped areas as well.

1942 USACE began construction on former cattle grazing land.

April 1942 The Ordnance Corps assumed responsibility for the depot.

1942 - 1946 The Chemical Weapons Munitions Burial Ground, located in the northeast portion of the installation, served as a burial site to destroy approximately 100 to 125 M-70 mustard-filled bombs.

1948 Ammunition workshop buildings were constructed for the renovation and demilitarization of ammunition.

1962 Pueblo Ordnance Depot was re-designated the Pueblo Army Depot under the newly created Supply and Maintenance Command, with consolidation of the Army Technical Services.

1965 – 1968 The former Mustard Disposal Area, located south of the North Burn Area 2 between gates 23 and 24, is a fenced area where mustard rounds were destroyed. Site history indicates the possibility of 7 disposal pits containing leaking HD rounds.

16 June 1976 Department of the Army Readiness Command (DARCOM) General orders No. 104 reassigned Pueblo to Tooele Army Depot as Pueblo Depot Activity.